Radiation dosimetry of [18F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans

Radiation dosimetry of [18F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans

Abstract Purpose (E)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-(3-(2-[18F]-fluoroethoxy)propyl) oxime ([18F]-PSS232) is a new PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGlu5), and has shown promising results in rodents and humans. The aim of this study was to estimate the...

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Bibliographic Details
Main Authors: Bert-Ram Sah, Michael Sommerauer, Linjing Mu, Gloria Pla Gonzalez, Susanne Geistlich, Valerie Treyer, Roger Schibli, Alfred Buck, Geoffrey Warnock, Simon M. Ametamey
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:EJNMMI Research
Subjects:
Dosimetry
Tracer
[18F]-PSS232
mGlu5 receptors
Online Access:http://link.springer.com/article/10.1186/s13550-019-0522-9

Internet

http://link.springer.com/article/10.1186/s13550-019-0522-9

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