Hypoxia Triggers TAZ Phosphorylation in Basal A Triple Negative Breast Cancer Cells

Hypoxia Triggers TAZ Phosphorylation in Basal A Triple Negative Breast Cancer Cells

Hypoxia and HIF signaling drive cancer progression and therapy resistance and have been demonstrated in breast cancer. To what extent breast cancer subtypes differ in their response to hypoxia has not been resolved. Here, we show that hypoxia similarly triggers HIF1 stabilization in luminal and basa...

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Bibliographic Details
Main Authors: Qiuyu Liu, Wanda van der Stel, Vera E. van der Noord, Hanneke Leegwater, Bircan Coban, Kim Elbertse, Joannes T. M. Pruijs, Olivier J. M. Béquignon, Gerard van Westen, Sylvia E. Le Dévédec, Erik H. J. Danen
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
hypoxia
breast cancer
TAZ
phosphorylation
basal A triple negative cells
Online Access:https://www.mdpi.com/1422-0067/23/17/10119

Internet

https://www.mdpi.com/1422-0067/23/17/10119

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