Using circulating O-sulfotyrosine in the differential diagnosis of acute kidney injury and chronic kidney disease

Using circulating O-sulfotyrosine in the differential diagnosis of acute kidney injury and chronic kidney disease

Abstract Background Sulfation of tyrosine, yielding O-sulfotyrosine, is a common but fixed post-translational modification in eukaryotes. Patients with increased circulating O-sulfotyrosine levels experience a faster decline in renal function with progression to end-stage renal disease (ESRD). In th...

Full description

Bibliographic Details
Main Authors: Shuai Chen, Yong-Hua Liu, Dao-Peng Dai, Zheng-Bin Zhu, Yang Dai, Zhi-Ming Wu, Li-Ping Zhang, Zhi-Feng Duan, Lin Lu, Feng-Hua Ding, Jin-Zhou Zhu, Rui-Yan Zhang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Nephrology
Subjects:
Acute kidney injury
Chronic kidney disease
Metabolite
Tyrosine O-sulfation
O-sulfotyrosine
Renal dysfunction
Online Access:https://doi.org/10.1186/s12882-021-02268-3

Internet

https://doi.org/10.1186/s12882-021-02268-3

Similar Items