Genetic Diversity in the Major Capsid L1 Protein of HPV-16 and HPV-18 in the Netherlands.

Genetic Diversity in the Major Capsid L1 Protein of HPV-16 and HPV-18 in the Netherlands.

Intratypic molecular variants of human papillomavirus (HPV) type-16 and -18 exist. In the Netherlands, a bivalent vaccine, composed of recombinant L1 proteins from HPV-16 and -18, is used to prevent cervical cancer since 2009. Long-term vaccination could lead to changes in HPV-16 and -18 virus popul...

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Bibliographic Details
Main Authors: Audrey J King, Jan A Sonsma, Henrike J Vriend, Marianne A B van der Sande, Mariet C Feltkamp, Hein J Boot, Marion P G Koopmans, Medical Microbiological Laboratories and Municipal Health Services
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4829201?pdf=render

Internet

http://europepmc.org/articles/PMC4829201?pdf=render

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