DisoFLAG: accurate prediction of protein intrinsic disorder and its functions using graph-based interaction protein language model

Abstract Intrinsically disordered proteins and regions (IDPs/IDRs) are functionally important proteins and regions that exist as highly dynamic conformations under natural physiological conditions. IDPs/IDRs exhibit a broad range of molecular functions, and their functions involve binding interactio...

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Bibliographic Details
Main Authors: Yihe Pang, Bin Liu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-023-01803-y