DisoFLAG: accurate prediction of protein intrinsic disorder and its functions using graph-based interaction protein language model
Abstract Intrinsically disordered proteins and regions (IDPs/IDRs) are functionally important proteins and regions that exist as highly dynamic conformations under natural physiological conditions. IDPs/IDRs exhibit a broad range of molecular functions, and their functions involve binding interactio...
Main Authors: | Yihe Pang, Bin Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
|
Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-023-01803-y |
Similar Items
-
Intrinsically Disordered Proteins: An Overview
by: Rakesh Trivedi, et al.
Published: (2022-11-01) -
Intrinsic Disorder in Tetratricopeptide Repeat Proteins
by: Nathan W. Van Bibber, et al.
Published: (2020-05-01) -
Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome
by: Maria de Lourdes Coelho Ribeiro, et al.
Published: (2013-02-01) -
Intrinsic Disorder in Proteins with Pathogenic Repeat Expansions
by: April L. Darling, et al.
Published: (2017-11-01) -
Comparative Assessment of Intrinsic Disorder Predictions with a Focus on Protein and Nucleic Acid-Binding Proteins
by: Akila Katuwawala, et al.
Published: (2020-12-01)