Newly Discovered Action of HpTx3 from Venom of Heteropoda <i>venatoria </i>on Na<sub>v</sub>1.7 and Its Pharmacological Implications in Analgesia
It has been reported that Heteropodatoxin3 (HpTx3), a peptidic neurotoxin purified from the venom of the spider species Heteropoda venatoria, could inhibit K<sub>v</sub>4.2 channels. Our present study newly found that HpTx3 also has potent and selective inhibitory action on Na<sub>...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-11-01
|
Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/11/12/680 |