During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ

During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ

Background: Characterising the correlates of HIV persistence improves understanding of disease pathogenesis and guides the design of curative strategies. This study investigated factors associated with integrated HIV-1 DNA load during consistently suppressive first-line antiretroviral therapy (ART)....

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Bibliographic Details
Main Authors: Alessandra Ruggiero, Ward De Spiegelaere, Alessandro Cozzi-Lepri, Maja Kiselinova, Georgios Pollakis, Apostolos Beloukas, Linos Vandekerckhove, Matthew Strain, Douglas Richman, Andrew Phillips, Anna Maria Geretti, Paola Vitiello, Nicola Mackie, Jonathan Ainsworth, Anele Waters, Frank Post, Simon Edwards, Julie Fox
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:EBioMedicine
Subjects:
Suppression
Reservoir
Persistence
Integration
Activation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300773

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http://www.sciencedirect.com/science/article/pii/S2352396415300773

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