Improved Synthesis of the Antitubercular Agent SQ109

We present here an improved procedure for the preparation of the promising antitubercular drug SQ109 that is currently in phase Ib/III of clinical trials against Mycobacterium tuberculosis. We investigated and tested the literature synthetic procedure that enables the development of structure–activi...

Full description

Bibliographic Details
Main Authors: Marianna Stampolaki, Antonios Kolocouris
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2021-12-01
Series:SynOpen
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-1655-5867