Evaluation of Deoxyribonucleic Acid Toxicity Induced by the Radiopharmaceutical 99mTechnetium-Methylenediphosphonic Acid and by Stannous Chloride in Wistar Rats

Evaluation of Deoxyribonucleic Acid Toxicity Induced by the Radiopharmaceutical 99mTechnetium-Methylenediphosphonic Acid and by Stannous Chloride in Wistar Rats

Radiopharmaceuticals are employed in patient diagnostics and disease treatments. Concerning the diagnosis aspect, technetium-99m (99mTc) is utilized to label radiopharmaceuticals for single photon computed emission tomography (SPECT) due to its physical and chemical characteristics. 99mTc fixation o...

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Bibliographic Details
Main Authors: Adriano Caldeira-de-Araujo, Mario Bernardo-Filho, Sebastião David Santos-Filho, Flavio José S. Dantas, Marcia Betânia Nunes de Oliveira, Vanessa Coutinho de Matos, Michelle Pinheiro Rodrigues, José Carlos Pelielo De Mattos
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Molecules
Subjects:
stannous chloride
99mTc-MDP
genotoxicity
mutagenicity
Comet assay
micronucleus test
Online Access:http://www.mdpi.com/1420-3049/17/11/12974

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http://www.mdpi.com/1420-3049/17/11/12974

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