Further Investigations of Nitroheterocyclic Compounds as Potential Antikinetoplastid Drug Candidates

Further Investigations of Nitroheterocyclic Compounds as Potential Antikinetoplastid Drug Candidates

Due to the lack of specific vaccines, management of the trypanosomatid-caused neglected tropical diseases (sleeping sickness, Chagas disease and leishmaniasis) relies exclusively on pharmacological treatments. Current drugs against them are scarce, old and exhibit disadvantages, such as adverse effe...

Full description

Bibliographic Details
Main Authors: Carlos García-Estrada, Yolanda Pérez-Pertejo, Bárbara Domínguez-Asenjo, Vanderlan Nogueira Holanda, Sankaranarayanan Murugesan, María Martínez-Valladares, Rafael Balaña-Fouce, Rosa M. Reguera
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
nitroheterocycles
kinetoplastids
sleeping sickness
Chagas disease
leishmaniasis
drug discovery
Online Access:https://www.mdpi.com/2218-273X/13/4/637

Internet

https://www.mdpi.com/2218-273X/13/4/637

Similar Items