Pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity

Abstract Pyk2 is a Ca2+-activated non-receptor tyrosine kinase enriched in the forebrain, especially in pyramidal neurons of the hippocampus. Previous reports suggested its role in hippocampal synaptic plasticity and spatial memory but with contradictory findings possibly due to experimental conditi...

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Bibliographic Details
Main Authors: Vincenzo Mastrolia, Omar al Massadi, Benoit de Pins, Jean-Antoine Girault
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95813-x