NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice

NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice

Abstract Previous studies suggested a beneficial effect of natriuretic peptides in animal models of cardiovascular disease, but the role of natriuretic peptide receptor C (NPRC) in the pathogenesis of atherosclerosis (AS) remains unknown. This study was designed to test the hypothesis that NPRC may...

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Bibliographic Details
Main Authors: Cheng Cheng, Jie Zhang, Xiaodong Li, Fei Xue, Lei Cao, Linlin Meng, Wenhai Sui, Meng Zhang, Yuxia Zhao, Bo Xi, Xiao Yu, Feng Xu, Jianmin Yang, Yun Zhang, Cheng Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01560-y

Internet

https://doi.org/10.1038/s41392-023-01560-y

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