Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration
Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Huntington’s disease (HD), are characterized by intracellular aggregation of proteins. In the case of ALS and FTD, these protein aggregates are found in the cytoplasm of affected neu...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-11-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/7/12/232 |