Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration

Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Huntington’s disease (HD), are characterized by intracellular aggregation of proteins. In the case of ALS and FTD, these protein aggregates are found in the cytoplasm of affected neu...

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Bibliographic Details
Main Authors: Birthe Fahrenkrog, Amnon Harel
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/7/12/232