The effect of non-specific binding of Pd(II) complexes with N-heteroaromatic hydrazone ligands on the protein structure

The effect of non-specific binding of Pd(II) complexes with N-heteroaromatic hydrazone ligands on the protein structure

Previously, the cytotoxic actions of five Pd(II) complexes with bidentate N-heteroaromatic chelators (complexes 1–5) on a palette of several cancer cell lines were investigated. However, the results of the cytotoxic activity did not correlate with the hydrophobic character of the complexes. To gain...

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Bibliographic Details
Main Authors: Mijin Nemanja D., Milošević Jelica, Filipović Nenad R., Mitić Dragana, Anđelković Katarina, Polović Natalija Đ., Todorović Tamara R.
Format: Article
Language:English
Published: Serbian Chemical Society 2022-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
ovalbumin model system
protein aggregation
dmso effect
ligand hydrophobicity
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2022/0352-51392200050M.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2022/0352-51392200050M.pdf

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