Comprehensive network medicine-based drug repositioning via integration of therapeutic efficacy and side effects

Abstract Despite advances in modern medicine that led to improvements in cardiovascular outcomes, cardiovascular disease (CVD) remains the leading cause of mortality and morbidity globally. Thus, there is an urgent need for new approaches to improve CVD drug treatments. As the development time and c...

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Bibliographic Details
Main Authors: Paola Paci, Giulia Fiscon, Federica Conte, Rui-Sheng Wang, Diane E. Handy, Lorenzo Farina, Joseph Loscalzo
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-022-00221-0