A genome-wide screen in macrophages identifies PTEN as required for myeloid restriction of Listeria monocytogenes infection.

A genome-wide screen in macrophages identifies PTEN as required for myeloid restriction of Listeria monocytogenes infection.

Listeria monocytogenes (Lm) is an intracellular foodborne pathogen which causes the severe disease listeriosis in immunocompromised individuals. Macrophages play a dual role during Lm infection by both promoting dissemination of Lm from the gastrointestinal tract and limiting bacterial growth upon i...

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Bibliographic Details
Main Authors: Rochelle C Glover, Nicole H Schwardt, Shania-Kate E Leano, Madison E Sanchez, Maureen K Thomason, Andrew J Olive, Michelle L Reniere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011058

Internet

https://doi.org/10.1371/journal.ppat.1011058

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