Transmigration of Trypanosoma brucei across an in vitro blood-cerebrospinal fluid barrier

Summary: Trypanosoma brucei is the causative agent of human African trypanosomiasis. The parasite transmigrates from blood vessels across the choroid plexus epithelium to enter the central nervous system, a process that leads to the manifestation of second stage sleeping sickness. Using an in vitro...

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Bibliographic Details
Main Authors: Annika Speidel, Marianne Theile, Lena Pfeiffer, Alexander Herrmann, Katherine Figarella, Hiroshi Ishikawa, Christian Schwerk, Horst Schroten, Michael Duszenko, Stefan Mogk
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422200284X