NSC‐34 motor neuron‐like cells are sensitized to ferroptosis upon differentiation

Ferroptosis is a form of regulated cell death that is driven by lethal accumulation of lipid peroxides upon inhibition of glutathione peroxidase 4 (GPx4). Deletion of the Gpx4 gene in mice revealed that neurons are sensitive to ferroptosis in vivo. However, few studies have been conducted on ferropt...

Full description

Bibliographic Details
Main Authors: Alejandra M. Martinez, Jovan Mirkovic, Zofia A. Stanisz, Fahmida S. Patwari, Wan Seok Yang
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12577