Structural Basis of Botulinum Toxin Type F Binding to Glycosylated Human SV2A: <i>In Silico</i> Studies at the Periphery of a Lipid Raft

Botulinum neurotoxins are the deadliest microbial neurotoxins in humans, with a lethal dose of 1 ng/kg. Incidentally, these neurotoxins are also widely used for medical and cosmetic purposes. However, little is known about the molecular mechanisms that control binding of botulinum neurotoxin type F1...

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Bibliographic Details
Main Authors: Fodil Azzaz, Didier Hilaire, Jacques Fantini
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/12/1821