Mathematical modeling of tumor therapy with oncolytic viruses: effects of parametric heterogeneity on cell dynamics

<p>Abstract</p> <p>Background:</p> <p>One of the mechanisms that ensure cancer robustness is tumor heterogeneity, and its effects on tumor cells dynamics have to be taken into account when studying cancer progression. There is no unifying theoretical framework in mathem...

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Bibliographic Details
Main Authors: Koonin Eugene V, Novozhilov Artem S, Karev Georgy P
Format: Article
Language:English
Published: BMC 2006-10-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/1/1/30