Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage

Abstract Clinical studies using suspensions or sheets of human pluripotent cell-derived retinal pigment epithelial cells (hiPSC-RPE) have been conducted globally for diseases such as age-related macular degeneration. Despite being minimally invasive, cell suspension transplantation faces challenges...

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Bibliographic Details
Main Authors: Keisuke Kajita, Mitsuhiro Nishida, Yasuo Kurimoto, Satoshi Yokota, Sunao Sugita, Toshika Semba, Satoshi Shirae, Naoko Hayashi, Atsuta Ozaki, Yoko Miura, Akiko Maeda, Yoshinori Mitamura, Masayo Takahashi, Michiko Mandai
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-60895-w