Mitochondrial Metabolomics of Sym1-Depleted Yeast Cells Revealed Them to Be Lysine Auxotroph

Mitochondrial Metabolomics of Sym1-Depleted Yeast Cells Revealed Them to Be Lysine Auxotroph

Metabolomics has expanded from cellular to subcellular level to elucidate subcellular compartmentalization. By applying isolated mitochondria to metabolome analysis, the hallmark of mitochondrial metabolites has been unraveled, showing compartment-specific distribution and regulation of metabolites....

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Bibliographic Details
Main Authors: Simon Lagies, Daqiang Pan, Daniel A. Mohl, Dietmar A. Plattner, Ian E. Gentle, Bernd Kammerer
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
compartment-specific metabolomics
mitochondria
yeast
sym1
lysine auxotroph
mitochondrial DNA depletion syndrome
Online Access:https://www.mdpi.com/2073-4409/12/5/692

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https://www.mdpi.com/2073-4409/12/5/692

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