Role of Murine Complement Component C5 in Acute in Vivo Infection by Pathogenic Leptospira interrogans

Role of Murine Complement Component C5 in Acute in Vivo Infection by Pathogenic Leptospira interrogans

Leptospirosis is considered one of the most important zoonosis worldwide. The activation of the Complement System is important to control dissemination of several pathogens in the host. Only a few studies have employed murine models to investigate leptospiral infection and our aim in this work was t...

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Bibliographic Details
Main Authors: Íris A. de Castro, Lorena Bavia, Tatiana R. Fraga, Mariane T. Amano, Leandro C. D. Breda, Adriana P. Granados-Martinez, Ana M. G. da Silva, Silvio A. Vasconcellos, Lourdes Isaac
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Complement System
C5
Leptospira
leptospirosis
murine model
inflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00063/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2018.00063/full

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