Inference of neuronal network spike dynamics and topology from calcium imaging data

Two-photon calcium imaging enables functional analysis of neuronal circuits by inferring action potential (AP) occurrence ('spike trains') from cellular fluorescence signals. It remains unclear how experimental parameters such as signal-to-noise ratio (SNR) and acquisition rate affec...

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Bibliographic Details
Main Authors: Henry eLütcke, Felipe eGerhard, Friedemann eZenke, Wulfram eGerstner, Fritjof eHelmchen
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00201/full