Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration

Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration

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Summary: Recent studies suggest that a western diet may contribute to clinical neurodegeneration and dementia. Adipocyte-specific expression of the Na,K-ATPase signaling antagonist, NaKtide, ameliorates the pathophysiological consequences of murine experimental obesity and renal failure. In this stu...

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Bibliographic Details
Main Authors: Komal Sodhi, Rebecca Pratt, Xiaoliang Wang, Hari Vishal Lakhani, Sneha S. Pillai, Mishghan Zehra, Jiayan Wang, Lawrence Grover, Brandon Henderson, James Denvir, Jiang Liu, Sandrine Pierre, Thomas Nelson, Joseph I. Shapiro
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Molecular physiology
Neuroscience
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221012311

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http://www.sciencedirect.com/science/article/pii/S2589004221012311

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