Coping with genetic diversity: the contribution of pathogen and human genomics to modern vaccinology

Vaccine development faces major difficulties partly because of genetic variation in both infectious organisms and humans. This causes antigenic variation in infectious agents and a high interindividual variability in the human response to the vaccine. The exponential growth of genome sequence inform...

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Bibliographic Details
Main Authors: D. Lemaire, T. Barbosa, P. Rihet
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000500001