Statistical analysis of synonymous and stop codons in pseudo-random and real sequences as a function of GC content

Abstract Knowledge of the frequencies of synonymous triplets in protein-coding and non-coding DNA stretches can be used in gene finding. These frequencies depend on the GC content of the genome or parts of it. An example of interest is provided by stop codons. This is relevant for the definition of...

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Bibliographic Details
Main Authors: Valentin Wesp, Günter Theißen, Stefan Schuster
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49626-9