Capsules with Ileocolonic-Targeted Release of Vitamin B<sub>2</sub>, B<sub>3</sub>, and C (ColoVit) Intended for Optimization of Gut Health: Development and Validation of the Production Process

Capsules with Ileocolonic-Targeted Release of Vitamin B<sub>2</sub>, B<sub>3</sub>, and C (ColoVit) Intended for Optimization of Gut Health: Development and Validation of the Production Process

The ileocolonic-targeted delivery of vitamins can establish beneficial alterations in gut microbial composition. Here, we describe the development of capsules containing riboflavin, nicotinic acid, and ascorbic acid covered with a pH-sensitive coating (ColoVit) to establish site-specific release in...

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Bibliographic Details
Main Authors: Aisha A. Ahmed, Antonius T. Otten, Bahez Gareb, Judith E. Huijmans, Anko C. Eissens, Ateequr Rehman, Gerard Dijkstra, Jos G. W. Kosterink, Henderik W. Frijlink, Reinout C. A. Schellekens
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
drug targeting
vitamin B<sub>2</sub>
vitamin B<sub>3</sub>
vitamin C
ileocolonic delivery
antioxidant
Online Access:https://www.mdpi.com/1999-4923/15/5/1354

Internet

https://www.mdpi.com/1999-4923/15/5/1354

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