Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates

Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates

Animal models are critical to understand disease and to develop countermeasures for the ongoing epidemics of Zika virus (ZIKV). Here we report a non-human primate model using a 2016 contemporary clinical isolate of ZIKV. Upon subcutaneous inoculation, rhesus macaques developed fever and viremia, wit...

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Bibliographic Details
Main Authors: Xiao-Feng Li, Hao-Long Dong, Xing-Yao Huang, Ye-Feng Qiu, Hong-Jiang Wang, Yong-Qiang Deng, Na-Na Zhang, Qing Ye, Hui Zhao, Zhong-Yu Liu, Hang Fan, Xiao-Ping An, Shi-Hui Sun, Bo Gao, Yun-Zhi Fa, Yi-Gang Tong, Fu-Chun Zhang, George F. Gao, Wu-Chun Cao, Pei-Yong Shi, Cheng-Feng Qin
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:EBioMedicine
Subjects:
Zika virus
Non-human primate model
Target organ
Lacrimal fluid
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416304431

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http://www.sciencedirect.com/science/article/pii/S2352396416304431

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