Comprehensive genomic analysis of primary bone sarcomas reveals different genetic patterns compared with soft tissue sarcomas

Comprehensive genomic analysis of primary bone sarcomas reveals different genetic patterns compared with soft tissue sarcomas

IntroductionSarcomas are classified into two types, bone sarcoma and soft tissue sarcoma (STS), which account for approximately 1% of adult solid malignancies and 20% of pediatric solid malignancies. There exist more than 50 subtypes within the two types of sarcoma. Each subtype is highly diverse an...

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Bibliographic Details
Main Authors: Qing Zhang, Yongkun Yang, Xia You, Yongzhi Ju, Qin Zhang, Tingting Sun, Weifeng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Oncology
Subjects:
sarcoma
mutation profile
microsatellite instability
therapeutic gene alteration
tumor mutation burden
PD-L1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1173275/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1173275/full

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