PEPITEM Treatment Ameliorates EAE in Mice by Reducing CNS Inflammation, Leukocyte Infiltration, Demyelination, and Proinflammatory Cytokine Production

PEPITEM Treatment Ameliorates EAE in Mice by Reducing CNS Inflammation, Leukocyte Infiltration, Demyelination, and Proinflammatory Cytokine Production

To investigate the effect of the therapeutic treatment of the immunopeptide, peptide inhibitor of trans-endothelial migration (PEPITEM) on the severity of disease in a mouse model of experimental autoimmune encephalomyelitis (EAE) as a model for human multiple sclerosis (MS), a series of experiments...

Full description

Bibliographic Details
Main Authors: Mohammed Alassiri, Fahd Al Sufiani, Mohammed Aljohi, Asma Alanazi, Aiman Saud Alhazmi, Bahauddeen M. Alrfaei, Hasan Alnakhli, Yasser A. Alshawakir, Saleh M. Alharby, Abdullah Y. Almubarak, Mohammed Alasseiri, Nora Alorf, Mashan L. Abdullah
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
EAE model
PEPITEM
demyelination
leukocyte trafficking
Online Access:https://www.mdpi.com/1422-0067/24/24/17243

Internet

https://www.mdpi.com/1422-0067/24/24/17243

Similar Items