Mining of transcriptome identifies CD109 and LRP12 as possible biomarkers and deregulation mechanism of T cell receptor pathway in Acute Myeloid Leukemia

Mining of transcriptome identifies CD109 and LRP12 as possible biomarkers and deregulation mechanism of T cell receptor pathway in Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) is a heterogeneous disease with highest mortality compared to other types of leukemia. There is a need to find the gene abnormalities and mechanisms behind them due to their heterogenic nature. The present study is aimed to understand genes, pathways and biomarker protei...

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Bibliographic Details
Main Authors: EbyNesar StellaGlory Deepak Shyl, Beutline Malgija, Appadurai Muthamil Iniyan, Ramasamy Mahendran, Samuel Gnana Prakash Vincent
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Heliyon
Subjects:
Acute myeloid leukemia
Network analysis
Differential gene expression
Gene ontology
Secretome analysis
Variant analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022024112

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http://www.sciencedirect.com/science/article/pii/S2405844022024112

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