Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies

Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies

IntroductionMesothelin (MSLN) is overexpressed in a wide variety of cancers with few therapeutic options and has recently emerged as an attractive target for cancer therapy, with a large number of approaches currently under preclinical and clinical investigation. In this respect, developing mesothel...

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Bibliographic Details
Main Authors: Abdennour Benloucif, Damien Meyer, Laure Balasse, Armelle Goubard, Lucile Danner, Ahlem Bouhlel, Rémy Castellano, Benjamin Guillet, Patrick Chames, Brigitte Kerfelec
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
mesothelin (MSLN)
nanobodies (Nbs)
positron emission tomography - computed tomography
fluorescence imaging
diagnostic
site-directed conjugation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1200652/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1200652/full

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