CD44 Suppression Improved the Chemosensitivity of HT-29 Colorectal Cancer Cells to 5-Fluorouracil and Inhibited Cell Migration

CD44 Suppression Improved the Chemosensitivity of HT-29 Colorectal Cancer Cells to 5-Fluorouracil and Inhibited Cell Migration

Purpose: CD44 plays a pivotal role through tumorigenesis by regulating cancer cell metastasis, stemness, and chemosensitivity and is considered a promising therapeutic target for human cancers, including colorectal cancer (CRC). Therefore, the present research aimed to examine the simultaneous thera...

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Bibliographic Details
Main Authors: Souzan Najafi, Zohreh Rahimi, Behzad Mansoori, Ali Mohammadi, Fatemeh Mohammadnejad, Mohammad Amini, Ahad Mokhtazadeh, Zahra Asadzadeh, William Chi-Shing Cho, Behzad Baradaran
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-07-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
cd44
5-fluorouracil
colorectal cancer
chemosensitivity
cell migration
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-13-551.pdf

Internet

https://apb.tbzmed.ac.ir/PDF/apb-13-551.pdf

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