High-Throughput Identification of MiR-145 Targets in Human Articular Chondrocytes

High-Throughput Identification of MiR-145 Targets in Human Articular Chondrocytes

MicroRNAs (miRNAs) play key roles in cartilage development and homeostasis and are dysregulated in osteoarthritis. MiR-145 modulation induces profound changes in the human articular chondrocyte (HAC) phenotype, partially through direct repression of <i>SOX9</i>. Since miRNAs can simultan...

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Bibliographic Details
Main Authors: Aida Martinez-Sanchez, Stefano Lazzarano, Eshita Sharma, Helen Lockstone, Christopher L. Murphy
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Life
Subjects:
miRNAs
chondrocyte
cartilage
RNA-immunoprecipitation
Online Access:https://www.mdpi.com/2075-1729/10/5/58

Internet

https://www.mdpi.com/2075-1729/10/5/58

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