Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends

Abstract Immune-checkpoint inhibitors (ICBs), in addition to targeting CTLA-4, PD-1, and PD-L1, novel targeting LAG-3 drugs have also been approved in clinical application. With the widespread use of the drug, we must deeply analyze the dilemma of the agents and seek a breakthrough in the treatment...

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Bibliographic Details
Main Authors: Qian Sun, Zhenya Hong, Cong Zhang, Liangliang Wang, Zhiqiang Han, Ding Ma
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01522-4