Plasma Kallikrein Cleaved H-kininogen: An End-Point Marker for Contact Activation in vitro and ex vivo

Plasma Kallikrein Cleaved H-kininogen: An End-Point Marker for Contact Activation in vitro and ex vivo

ObjectivesThe contact system consists of coagulation factor XII (FXII), prekallikrein, and H-kininogen (HK) and plays important roles in many diseases. Plasma kallikrein (PKa) cleaved HK (cHK) is a marker of contact activation. Presently, we developed a specific and precise enzyme-linked immunosorbe...

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Bibliographic Details
Main Authors: Yaseelan Palarasah, Stephanie Thuy Duong Pham, Jørgen Brodersen Gram, Jonas Heilskov Graversen, Katrine Pilely, Johannes Jakobsen Sidelmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
contact system
specific antibody
cleaved H-kininogen
ELISA
reference interval
blood contacting biomaterials
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.873975/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.873975/full

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