Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity

Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity

Microglia, the resident immune cells of the brain, play important roles in defending the brain against pathogens and supporting neuronal circuit plasticity. Chronic or excessive pro-inflammatory responses of microglia damage neurons, therefore their activity is tightly regulated. Pharmacological and...

Full description

Bibliographic Details
Main Authors: Frank Ativie, Joanna A. Komorowska, Eva Beins, Önder Albayram, Till Zimmer, Andreas Zimmer, Dario Tejera, Michael Heneka, Andras Bilkei-Gorzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
microglia activity
GABAergic neurons
CB1 cannabinoid receptor
LPS stimulation
cytokine expression
morphology and size
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00295/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00295/full

Similar Items