Periodic temperature changes drive the proliferation of self-replicating RNAs in vesicle populations

How primordial cells could achieve inheritance of encapsulated components is still an open question. Here, the authors show that ribozymes can assemble in active forms and replicate in populations of membrane vesicles thanks to freeze-thaw cycles.

Bibliographic Details
Main Authors: Elia Salibi, Benedikt Peter, Petra Schwille, Hannes Mutschler
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36940-z