Predicting gene expression from histone modifications with self-attention based neural networks and transfer learning

It is well known that histone modifications play an important part in various chromatin-dependent processes such as DNA replication, repair, and transcription. Using computational models to predict gene expression based on histone modifications has been intensively studied. However, the accuracy of...

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Bibliographic Details
Main Authors: Yuchi Chen, Minzhu Xie, Jie Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1081842/full