Phosphatidylserine receptors enhance SARS-CoV-2 infection.

Phosphatidylserine receptors enhance SARS-CoV-2 infection.

Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through virion-associated PS binding that is termed apoptotic mimicry. Here we show that this broadly shared uptake mechanism is utilized by SARS-CoV-2 in cells that express low surface levels of ACE2. Expression of member...

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Bibliographic Details
Main Authors: Dana Bohan, Hanora Van Ert, Natalie Ruggio, Kai J Rogers, Mohammad Badreddine, José A Aguilar Briseño, Jonah M Elliff, Roberth Anthony Rojas Chavez, Boning Gao, Tomasz Stokowy, Eleni Christakou, Petri Kursula, David Micklem, Gro Gausdal, Hillel Haim, John Minna, James B Lorens, Wendy Maury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009743

Internet

https://doi.org/10.1371/journal.ppat.1009743

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