Regulation of PDGFRα+ cells and ICC in progesterone-mediated slow colon transit in pregnant mice

Regulation of PDGFRα+ cells and ICC in progesterone-mediated slow colon transit in pregnant mice

Background: Progesterone can inhibit intestinal smooth muscle contraction; however, the specific mechanism remains unclear. Besides smooth muscle cells, smooth muscle has two important mesenchymal cells, namely interstitial cells of Cajal (ICC) and PDGFRα+ cells, which induce the contraction and rel...

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Bibliographic Details
Main Authors: Chen Lu, Hui Luo, Ye Wang, Shuang Jing, Jun Zhao, Kexin Zou, Fan Wu, Hao Ying
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Progesterone
PDGFRα+ cell
ICC
Colon slow transit
Smooth muscle
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024012581

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http://www.sciencedirect.com/science/article/pii/S2405844024012581

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