Structural insight into broadening SARS-CoV-2 neutralization by an antibody cocktail harbouring both NTD and RBD potent antibodies

Structural insight into broadening SARS-CoV-2 neutralization by an antibody cocktail harbouring both NTD and RBD potent antibodies

The continual emergence of highly pathogenic novel coronaviruses and their variants has underscored the importance of neutralizing monoclonal antibodies (mAbs) as a pivotal therapeutic approach. In the present study, we report the specific neutralizing antibodies 13H7 and 9G11, which target the N-te...

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Bibliographic Details
Main Authors: Wenling Jiang, Yanan Jiang, Hui Sun, Tingting Deng, Kunyu Yu, Qianjiao Fang, Huimin Ge, Miaoling Lan, Yanling Lin, Zhongyue Fang, Yali Zhang, Lizhi Zhou, Tingting Li, Hai Yu, Qingbing Zheng, Shaowei Li, Ningshao Xia, Ying Gu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
NTD and RBD
neutralizing monoclonal antibodies
antibody cocktails
omicron variants
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2406300

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2024.2406300

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