DUBs, new members in the hypoxia signaling clUb
Cellular protein homeostasis is tightly regulated by ubiquitination. Responsible for target protein ubiquitination is a class of enzymes, the so-called ubiquitin (Ub) E3-ligases. They are opposed to a second class of enzymes, called DeUBiquitinating enzymes (DUBs), which can remove polyubiquitin cha...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-03-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00053/full |