Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis

Abstract Leishmaniasis is one of the top neglected tropical diseases with significant morbidity and mortality in low and middle-income countries (LMIC). However, this disease is also spreading in the developed world. Currently, there is a lack of effective strategies to control this disease. Vaccina...

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Bibliographic Details
Main Authors: Subir Karmakar, Greta Volpedo, Wen-Wei Zhang, Patrick Lypaczewski, Nevien Ismail, Fabiano Oliveira, James Oristian, Claudio Meneses, Sreenivas Gannavaram, Shaden Kamhawi, Shinjiro Hamano, Jesus G. Valenzuela, Greg Matlashewski, Abhay R. Satoskar, Ranadhir Dey, Hira L. Nakhasi
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00574-x