Pannexin 1 dysregulation in Duchenne muscular dystrophy and its exacerbation of dystrophic features in mdx mice

Pannexin 1 dysregulation in Duchenne muscular dystrophy and its exacerbation of dystrophic features in mdx mice

Abstract Background Duchenne muscular dystrophy (DMD) is associated with impaired muscle regeneration, progressive muscle weakness, damage, and wasting. While the cause of DMD is an X-linked loss of function mutation in the gene encoding dystrophin, the exact mechanisms that perpetuate the disease p...

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Bibliografski detalji
Glavni autori: Emily Freeman, Stéphanie Langlois, Marcos F. Leyba, Tarek Ammar, Zacharie Léger, Hugh J. McMillan, Jean-Marc Renaud, Bernard J. Jasmin, Kyle N. Cowan
Format: Članak
Jezik:English
Izdano: BMC 2024-04-01
Serija:Skeletal Muscle
Teme:
Duchenne muscular dystrophy
Myoblast
Myofiber
Pannexin 1
Skeletal muscle
Online pristup:https://doi.org/10.1186/s13395-024-00340-8

Internet

https://doi.org/10.1186/s13395-024-00340-8

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