Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein

Paediatric cancers commonly harbour quiet mutational landscapes and are instead characterized by single driver events such as the mutation of critical chromatin regulators, expression of oncohistones, or expression of oncogenic fusion proteins. These events ultimately promote malignancy through disr...

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Bibliographic Details
Main Authors: Emily R. Theisen, Julia Selich-Anderson, Kyle R. Miller, Jason M. Tanner, Cenny Taslim, Kathleen I. Pishas, Sunil Sharma, Stephen L. Lessnick
Format: Article
Language:English
Published: Taylor & Francis Group 2021-04-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2020.1805678