A Novel Mutation of <i>MSH2</i> Gene in a Patient with Lynch Syndrome Presenting with Thirteen Metachronous Malignancies

A Novel Mutation of <i>MSH2</i> Gene in a Patient with Lynch Syndrome Presenting with Thirteen Metachronous Malignancies

Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), accounts for 2–3% of all colorectal cancers. This autosomal dominant disorder is associated with a predisposition to endometrial, stomach, small bowel, pancreatic, biliary tract, ovary, urinary tract, brain, and sk...

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Bibliographic Details
Main Authors: Ugne Silinskaite, Edita Gavelienė, Rokas Stulpinas, Ramunas Janavicius, Tomas Poskus
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Journal of Clinical Medicine
Subjects:
lynch syndrome
hereditary nonpolyposis colorectal cancer
metachronous cancer
multiple malignancies
tumor
surveillance
Online Access:https://www.mdpi.com/2077-0383/12/17/5502

Internet

https://www.mdpi.com/2077-0383/12/17/5502

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