Discreteness of cell–surface contacts affects spatio-temporal dynamics, adhesion, and proliferation of mouse embryonic stem cells

Discreteness of cell–surface contacts affects spatio-temporal dynamics, adhesion, and proliferation of mouse embryonic stem cells

The self-renewal and lineage-specific differentiation of stem cells are regulated by interactions with their microenvironments, called stem cell niche. Stem cells receive both biochemical and biophysical cues from their niche, which leads to the activation of signaling pathways, resulting in the mod...

Full description

Bibliographic Details
Main Authors: Esther Kimmle, Zahra Hajian Foroushani, Stephan Keppler, Judith Thoma, Kentaro Hayashi, Akihisa Yamamoto, Martin Bastmeyer, Motomu Tanaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Physics
Subjects:
mouse embryonic stem cell
nanofiber
cell migration
active deformation
adhesion
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.1052106/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2022.1052106/full

Similar Items